Kaplan-Messas Audrey, Cohen Yuval, Blumenthal Eytan, Avni Isaac
Department of Ophthalmology, Assaf Harofeh Medical Center, Zerifin, affiliated with the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv - Israel.
Eur J Ophthalmol. 2009 Mar-Apr;19(2):231-4. doi: 10.1177/112067210901900209.
To compare the 1-year outcome of trabeculectomy and combined phaco-trabeculectomy that were performed with or without a peripheral iridectomy (PI).
In a large tertiary glaucoma clinic, with a single surgeon performing all surgeries, 47 patients scheduled to undergo either a primary trabeculectomy or phaco-trabeculectomy were prospectively randomized to surgery with or without peripheral iridectomy. Other than the inclusion (PI group) or omission (no PI group) of a PI, surgical technique and postoperative care were identical for the two groups. The two groups were compared for intraocular pressure (IOP), success rates, visual acuity (VA), and complication rates. Complete and qualified success rates were defined as IOP 18 mmHg or less with or without medications, respectively.
The 1-year complete and qualified success rates were comparable for both groups. Complete success was observed in 70% of cases, and qualified success in more than 90%. One patient (4.3%) from the no-PI group developed an iris incarceration into the internal sclerectomy site on postoperative day 1, requiring surgical intervention. No other significant complications (blebitis, endophthalmitis, or choroidal hemorrhage) were encountered in any of the study patients.
This randomized prospective small scale study explored the possibility of sparing the need to perform a routine PI in trabeculectomy and phaco-trabeculectomy. These preliminary results suggest that the outcomes in the two groups are comparable, paving the way to a larger scale study evaluating the need for PI in modern trabeculectomy surgery.
比较小梁切除术和白内障超声乳化吸除联合小梁切除术在有或无周边虹膜切除术(PI)情况下的1年手术效果。
在一家大型三级青光眼诊所,由同一位外科医生进行所有手术,47例计划接受原发性小梁切除术或白内障超声乳化吸除联合小梁切除术的患者被前瞻性随机分为有或无周边虹膜切除术的手术组。除了是否包含周边虹膜切除术(PI组或无PI组)外,两组的手术技术和术后护理相同。比较两组的眼压(IOP)、成功率、视力(VA)和并发症发生率。完全成功率和合格成功率分别定义为使用或不使用药物时眼压≤18 mmHg。
两组的1年完全成功率和合格成功率相当。70%的病例观察到完全成功,超过90%的病例为合格成功。无PI组的1例患者(4.3%)在术后第1天出现虹膜嵌顿于巩膜内切除部位,需要手术干预。在任何研究患者中均未遇到其他严重并发症(睑缘炎、眼内炎或脉络膜出血)。
这项随机前瞻性小规模研究探讨了在小梁切除术和白内障超声乳化吸除联合小梁切除术中无需常规进行周边虹膜切除术的可能性。这些初步结果表明两组的手术效果相当,为评估现代小梁切除术是否需要进行周边虹膜切除术的大规模研究铺平了道路。