年龄相关性黄斑变性所致脉络膜新生血管患者的瞳孔测量特征
Pupillometric characteristics in patients with choroidal neovascularization due to age-related macular degeneration.
作者信息
Brozou Catherine, Fotiou Dimitrios, Androudi Sofia, Theodoridou Evelyn, Giantselidis Charalambos, Alexandridis Alexandros, Brazitikos Periklis
机构信息
Laboratory of Clinical Neurophysiology, Aristotle University of Thessaloniki, Thessaloniki - Greece.
出版信息
Eur J Ophthalmol. 2009 Mar-Apr;19(2):254-62. doi: 10.1177/112067210901900213.
PURPOSE
To study the pupillary light reflex in patients with choroidal neovascularization due to age-related macular degeneration (AMD).
METHODS
The study included 15 patients with AMD and 15 control subjects. A full recording of the pupil's reaction to light was registered and the following eight parameters were measured and reported: baseline pupil (R1), latency (T1), minimum pupil radius (R2), amplitude (AMP), maximum constriction velocity (VCmax), maximum constriction acceleration (ACmax), time for maximum velocity (T2), and time for maximum constriction (T3).
RESULTS
All variables measured presented alterations in the AMD group and a number of them were significantly reduced in the AMD group.
CONCLUSIONS
The presence of neovascular AMD significantly affects the pupil's response to light stimulus when compared to normal subjects.
目的
研究年龄相关性黄斑变性（AMD）所致脉络膜新生血管患者的瞳孔光反射。
方法
该研究纳入了15例AMD患者和15例对照受试者。对瞳孔对光的反应进行了完整记录，并测量和报告了以下八个参数：基线瞳孔（R1）、潜伏期（T1）、最小瞳孔半径（R2）、幅度（AMP）、最大收缩速度（VCmax）、最大收缩加速度（ACmax）、达到最大速度的时间（T2）和达到最大收缩的时间（T3）。
结果
AMD组测量的所有变量均出现改变，其中一些变量在AMD组显著降低。
结论
与正常受试者相比，新生血管性AMD的存在显著影响瞳孔对光刺激的反应。
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