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[肝泡型包虫病]

[Hepatic alveolar echinococcosis].

作者信息

Gillet M, Bresson-Hadni S

机构信息

Service de chirurgie digestive, hôpital Jean-Minjoz, Besançon.

出版信息

Rev Prat. 1991 Sep 1;41(19):1805-11.

PMID:1925360
Abstract

Alveolar echinococcosis (AE) is an uncommon parasitic disease that is caused by the intrahepatic growth of Echinococcus multilocularis larvae. Eastern France is endemic for AE. A wild cycle allows the parasite to subsist in nature. The adult worm develops in the small intestine of foxes. The eggs of the taenia are dispersed on the ground by the foxes' stools. Rodents are infested by eating contaminated vegetables and larvae develop in the liver. Humans, accidental intermediate hosts, become infested due to either eating contaminated wild fruits, or by touching foxes or dogs. The human lesions of AE are often compared to a liver cancer which progress very slowly, causing necrosis and fibrosis. Complications invariably occurred during the follow-up. The most frequent are biliary complications, bleeding related to portal hypertension or Budd Chiari syndrome. During the last years, important progress has been made in many fields concerning AE, particularly in the immunology, epidemiology and therapy of this disease. The sole efficient treatment is partial hepatectomy. Recently, liver transplantation have been successfully performed for incurable AE.

摘要

肺泡型棘球蚴病(AE)是一种由多房棘球绦虫幼虫在肝脏内生长引起的罕见寄生虫病。法国东部是AE的流行地区。野生传播循环使寄生虫能够在自然界中生存。成虫在狐狸的小肠内发育。绦虫卵通过狐狸的粪便散布在地面上。啮齿动物因食用受污染的蔬菜而感染,幼虫在肝脏内发育。人类作为偶然的中间宿主,因食用受污染的野生水果或接触狐狸或狗而感染。AE的人类病变常被比作进展非常缓慢的肝癌,会导致坏死和纤维化。随访期间总会出现并发症。最常见的是胆道并发症、与门静脉高压或布加综合征相关的出血。在过去几年里,在AE的许多领域都取得了重要进展,特别是在这种疾病的免疫学、流行病学和治疗方面。唯一有效的治疗方法是肝部分切除术。最近,肝移植已成功用于无法治愈的AE。

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Rev Prat. 1991 Sep 1;41(19):1805-11.
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[The so-called "fox tapeworm"].[所谓的“狐绦虫”]
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