Limaïem F, Ayadi-Kaddour A, Aissa I, Marghli A, Ghedira H, El Mezni F
Department of Pathology, Abderrahmen Mami Hospital Ariana, Tunisia.
Pathologica. 2008 Oct;100(5):424-7.
Desmoid tumour is an uncommon, locally invasive non-metastasizing neoplastic lesion. The pathogenesis of this tumour is unclear and its treatment is controversial. In this paper, the authors report a new case of chest wall desmoid tumour in a 67-year-old man previously operated by sternotomy for a triple aortocoronary bypass. To the best of our knowledge only two cases of thoracic desmoid tumours following aortocoronary bypass have been reported in literature. The correlation between the site of the surgical approach and the tumour, and the time interval between surgery and presentation, supports the hypothesis of a causal role of surgical trauma in the occurrence of this tumour. The Authors discuss the pathogenesis of this tumour with review of the current literature.
硬纤维瘤是一种罕见的、局部侵袭性的非转移性肿瘤性病变。该肿瘤的发病机制尚不清楚，其治疗方法存在争议。在本文中，作者报告了一例67岁男性胸壁硬纤维瘤的新病例，该患者此前因三支冠状动脉搭桥术接受过胸骨切开术。据我们所知，文献中仅报道了两例冠状动脉搭桥术后发生胸段硬纤维瘤的病例。手术入路部位与肿瘤之间的相关性，以及手术与肿瘤出现之间的时间间隔，支持了手术创伤在该肿瘤发生中起因果作用的假说。作者结合当前文献讨论了该肿瘤的发病机制。
