Cheepsattayakorn Attapon, Tharavichitakul Prasit, Dettrairat Sakchai, Sutachai Vorasak
10th Zonal Tuberculosis and Chest Disease Center, Chiang Mai, 10th Office of Disease Prevention and Control, Department of Disease Control, Ministry of Public Health, Thailand.
J Med Assoc Thai. 2009 Feb;92(2):284-9.
Moraxella catarrhalis pneumonia, although in the immunocompromised patients is very uncommon for community-acquired pneumonia (CAP). It demonstrates a potential pathogen with high mortality when the presence of heavy numbers of organisms, intracellularly and extracellularly, in the sputum Gram's stained smears confirmed by cultures. In 2007, the authors reported a case of a 28-year-old Thai single male patient with acquired-immunodeficiency syndrome (AIDS) and Moraxella catarrhalis pneumonia who dramatically responded to two weeks of oral Amoxyclav (Amoxycillin trihydrate 500 milligrams + Clavulanic acid (Potassium clavulanate) 125 milligrams) treatment at 625 milligrams every 8 hours and then discharged. The present case report describes clinical and initial chest roentgenographic presentations of Moraxella catarrhalis pneumonia in AIDS patient. The importance of chest roentgenographic pictures, CD4/CD8-T lymphocyte ratio, sputum Gram's stainings, cultures with susceptibility testing in establishing a diagnosis, and protective vaccine are discussed.
卡他莫拉菌肺炎,尽管在免疫功能低下的患者中对于社区获得性肺炎(CAP)来说非常罕见。当痰革兰氏染色涂片经培养证实细胞内和细胞外存在大量该菌时,它是一种具有高死亡率的潜在病原体。2007年,作者报道了一例28岁的泰国单身男性艾滋病患者合并卡他莫拉菌肺炎,该患者对每8小时口服625毫克的阿莫西林克拉维酸(三水合阿莫西林500毫克 + 克拉维酸(克拉维酸钾)125毫克)进行为期两周的治疗反应显著,随后出院。本病例报告描述了艾滋病患者卡他莫拉菌肺炎的临床及初始胸部X线表现。讨论了胸部X线片、CD4/CD8-T淋巴细胞比值、痰革兰氏染色、培养及药敏试验在确立诊断中的重要性以及保护性疫苗。