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Triiodothyronine receptors during maturation.

作者信息

DeGroot L J, Robertson M, Rue P A

出版信息

Endocrinology. 1977 Jun;100(6):1511-5. doi: 10.1210/endo-100-6-1511.

DOI:10.1210/endo-100-6-1511
PMID:192539
Abstract

Capacity of rat liver nuclear triiodothyronine (T3) binding protein (NTBP) for T3 more than quadruples from birth through 50-120 days, whether related to DNA or weight of tissue. Ka for T3 doubles during this interval. T3 content of nuclei nearly parallels capacity. The proportion of receptors occupied by T3 is 0.3 at birth, falling to .16 in old rats. In contrast to these changes in liver content of T3-receptor complex, mitochondrial alpha-glycerophosphate dehydrogenase activity changes relatively less during maturation. Administration of estrogen, testosterone, and dexamethasone to immature female rats did not alter NTBP capacity of affinity.

摘要

相似文献

1
Triiodothyronine receptors during maturation.
Endocrinology. 1977 Jun;100(6):1511-5. doi: 10.1210/endo-100-6-1511.
2
[Increased liver nuclear triiodothyronine-receptors associated with mitochondrial alpha-glycerophosphate dehydrogenase activity in hyperthyroid rats (author's transl)].甲状腺功能亢进大鼠肝脏细胞核三碘甲状腺原氨酸受体增加与线粒体α-甘油磷酸脱氢酶活性相关（作者译）
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3
Analysis of nuclear 5,5,3'-triiodothyronine-binding capacity and tissue response in the liver of the neonatal rat.
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5
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[Sequential changes in the nuclear triiodothyronine receptors and mitochondrial alpha-glycerophosphate dehydrogenase activity after the administration of triiodothyronine (author's transl)].
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Sex-related differences in the activity of liver mitochondrial alpha-glycerophosphate dehydrogenase in the rat.大鼠肝脏线粒体α-磷酸甘油脱氢酶活性的性别相关差异。
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引用本文的文献

1
Thyroid state and mitochondrial population during maturation and ageing.
J Endocrinol Invest. 1980 Jul-Sep;3(3):293-6. doi: 10.1007/BF03348278.
2
Thyroid state and mitochondrial population during cold exposure.冷暴露期间的甲状腺状态与线粒体数量
Pflugers Arch. 1983 Jan;396(1):49-53. doi: 10.1007/BF00584697.
3
Effect of hypothyroidism on the biogenesis of free mitochondria in the cerebral hemispheres and in cerebellum of rat during postnatal development.甲状腺功能减退对大鼠出生后发育过程中大脑半球和小脑中游离线粒体生物合成的影响。
Neurochem Res. 1985 Feb;10(2):163-77. doi: 10.1007/BF00964565.
4
T3 receptor occupancy and metabolic responses.T3受体占有率与代谢反应。
J Endocrinol Invest. 1979 Apr-Jun;2(2):183-9. doi: 10.1007/BF03349311.
5
Nuclear receptors for thyroid hormone.甲状腺激素的核受体
J Endocrinol Invest. 1978 Jan;1(1):79-88. doi: 10.1007/BF03346775.