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中风后肩部疼痛的肩峰下皮质类固醇注射:一项探索性前瞻性病例系列研究。

Subacromial corticosteroid injection for poststroke shoulder pain: an exploratory prospective case series.

作者信息

Chae John, Jedlicka Lynn

机构信息

Department of Physical Medicine and Rehabilitation, Case Western Reserve University School of Medicine, MetroHealth Rehabilitation Institute of Ohio, Cleveland, OH 44109, USA.

出版信息

Arch Phys Med Rehabil. 2009 Mar;90(3):501-6. doi: 10.1016/j.apmr.2008.10.011.

Abstract

OBJECTIVE

To assess the effectiveness of subacromial corticosteroid injections for poststroke shoulder pain.

DESIGN

Exploratory, prospective case series.

SETTING

Ambulatory setting, university-affiliated hospital.

PARTICIPANTS

Stroke survivors (N=10) with pain in the hemiparetic shoulder.

INTERVENTION

Consecutive stroke survivors with evidence of supraspinatus impingement, supraspinatus tendonitis, or subacromial bursitis received subacromial corticosteroid injections.

MAIN OUTCOME MEASURES

The primary outcome measure was the Brief Pain Inventory (BPI) question 12 (BPI 12), which assesses "worst pain" in the previous 7 days. Secondary measures included BPI question 15, which assesses present pain and BPI question 23 (BPI 23), which assesses pain interference with 7 daily activities. Outcomes were assessed at baseline, weekly for the first 4 weeks and then at 8 and 12 weeks postinjection.

RESULTS

Repeated measure analysis of variance revealed significant within group time effect for BPI 12 (F=7.7, P<.001). Based on absolute means, the largest therapeutic benefit was seen by the second week postinjection with partial loss of effect thereafter. There were significant within group time effects for the general activity (F=3.2, P=.009), sleep (F=3.9, P=.003), and enjoyment of life (F=2.3, P=.044) domains of BPI 23.

CONCLUSIONS

Subacromial corticosteroid injection is associated with significant reduction in poststroke shoulder pain in patients with evidence of supraspinatus impingement, supraspinatus tendonitis, or subacromial bursitis. However, there is a gradual loss of effect with time. Controlled trials are needed to show a cause and effect relationship.

摘要

目的

评估肩峰下皮质类固醇注射治疗中风后肩部疼痛的有效性。

设计

探索性前瞻性病例系列研究。

地点

大学附属医院门诊。

参与者

10名偏瘫肩部疼痛的中风幸存者。

干预措施

对有冈上肌撞击、冈上肌腱炎或肩峰下滑囊炎证据的连续中风幸存者进行肩峰下皮质类固醇注射。

主要观察指标

主要观察指标为简明疼痛量表(BPI)第12题(BPI 12),评估前7天的“最痛程度”。次要指标包括评估当前疼痛的BPI第15题和评估疼痛对7项日常活动干扰程度的BPI第23题(BPI 23)。在基线、注射后的前4周每周评估一次,然后在注射后8周和12周进行评估。

结果

重复测量方差分析显示,BPI 12在组内时间效应显著(F=7.7,P<0.001)。基于绝对均值,注射后第二周观察到最大治疗效果,此后效果部分丧失。BPI 23的一般活动(F=3.2,P=0.009)、睡眠(F=3.9,P=0.003)和生活乐趣(F=2.3,P=0.044)领域在组内时间效应显著。

结论

对于有冈上肌撞击、冈上肌腱炎或肩峰下滑囊炎证据的患者,肩峰下皮质类固醇注射可显著减轻中风后肩部疼痛。然而,随着时间推移效果会逐渐丧失。需要进行对照试验来证明因果关系。

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