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乳腺癌质量控制。

Breast cancer quality control.

作者信息

Patterson Cam, Ronnebaum Sarah

机构信息

Division of Cardiology and Carolina Cardiovascular Biology Center, University of North Carolina at Chapel Hill, 8200 Medical Biomolecular Research Building, Chapel Hill, North Carolina 27599-7126, USA.

出版信息

Nat Cell Biol. 2009 Mar;11(3):239-41. doi: 10.1038/ncb0309-239.

Abstract

Tumorigenesis is regulated by several mechanisms including signalling, transcription and DNA replication. Now a cytoplasmic protein quality-control pathway is implicated in the suppression of breast cancer cell growth, suggesting a new role for quality-control mechanisms in suppressing cells with malignant potential.

摘要

肿瘤发生受多种机制调控,包括信号传导、转录和DNA复制。现在,一种细胞质蛋白质质量控制途径与抑制乳腺癌细胞生长有关,这表明质量控制机制在抑制具有恶性潜能的细胞方面具有新作用。

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