Stehling M K, Turner R, Mansfield P
Department of Cardiology, Friedrich Alexander University, Erlangen, Germany.
Science. 1991 Oct 4;254(5028):43-50. doi: 10.1126/science.1925560.
Progress has recently been made in implementing magnetic resonance imaging (MRI) techniques that can be used to obtain images in a fraction of a second rather than in minutes. Echo-planar imaging (EPI) uses only one nuclear spin excitation per image and lends itself to a variety of critical medical and scientific applications. Among these are evaluation of cardiac function in real time, mapping of water diffusion and temperature in tissue, mapping of organ blood pool and perfusion, functional imaging of the central nervous system, depiction of blood and cerebrospinal fluid flow dynamics, and movie imaging of the mobile fetus in utero. Through shortened patient examination times, higher patient throughput, and lower cost per MRI examination, EPI may become a powerful tool for early diagnosis of some common and potentially treatable diseases such as ischemic heart disease, stroke, and cancer.
近年来，在实施磁共振成像（MRI）技术方面取得了进展，该技术可用于在几分之一秒而非几分钟内获取图像。回波平面成像（EPI）每张图像仅使用一次核自旋激发，适用于各种关键的医学和科学应用。其中包括实时评估心脏功能、绘制组织中的水扩散和温度图、绘制器官血池和灌注图、中枢神经系统的功能成像、描绘血液和脑脊液流动动力学，以及子宫内活动胎儿的电影成像。通过缩短患者检查时间、提高患者通量以及降低每次MRI检查的成本，EPI可能成为早期诊断某些常见且可能可治疗疾病（如缺血性心脏病、中风和癌症）的有力工具。
