Badmos K B, Sabageh D, Ojo O S, Balogun O S
Department of Pathology, College of Health Sciences, University of Ilorin, Ilorin, Kwara State.
West Afr J Med. 2008 Jul;27(3):175-7.
Eosinophilic colitis is an inflammatory condition characterized by infiltration of the colonic wall by eosinophils with submucosal oedema. Involvement of caecum, appendix, ascending colon and the omentum by the inflammatory process could mimic a right iliac fossa neoplasm.
To highlight the diagnostic challenges posed by eosinophilic colitis and the import of histopathological diagnosis in the treatment of such a patient.
A47-year old perimenopausal woman presented to hospital with a 6-month history of intermittent lower abdominal pain. Besides clinical evaluation, an abdominal ultrasonography and full blood count were carried out. She subsequently had exploratory laparatomy.
The lower abdominal pain was intermittent but not associated with vomiting or diarrhea. There was a tender right iliac mass extending to the suprapubic region. The ultrasound revealed a right-sided tubo-ovarian mass. At surgery, the mass was found to be a complex of caecum, ascending colon, appendix and the omentum. Histological diagnosis of the resected mass was eosinophilic colitis with peritonitis. She was placed on steroid therapy following a course of antihelminthics with sustained clinical improvement six months after surgery.
Eosinophilic colitis is rare and could mimic a right iliac neoplasm if it is right-sided. Histopathological diagnosis of all specimens removed at surgery particularly in a peripheral district hospital is very important in patient's management.
嗜酸性粒细胞性结肠炎是一种炎症性疾病,其特征为嗜酸性粒细胞浸润结肠壁并伴有黏膜下水肿。炎症过程累及盲肠、阑尾、升结肠和网膜时,可能会被误诊为右下腹肿瘤。
强调嗜酸性粒细胞性结肠炎带来的诊断挑战以及组织病理学诊断在这类患者治疗中的重要性。
一名47岁围绝经期女性因间歇性下腹痛6个月入院。除临床评估外,还进行了腹部超声检查和全血细胞计数。随后她接受了剖腹探查术。
下腹部疼痛呈间歇性,但与呕吐或腹泻无关。右下腹有一压痛性肿块,延伸至耻骨上区域。超声显示右侧输卵管卵巢肿块。手术中发现该肿块是由盲肠、升结肠、阑尾和网膜组成的复合体。切除肿块的组织学诊断为嗜酸性粒细胞性结肠炎伴腹膜炎。在接受了一个疗程的抗蠕虫药物治疗后,她接受了类固醇治疗,术后6个月临床症状持续改善。
嗜酸性粒细胞性结肠炎较为罕见,如果发生在右侧,可能会被误诊为右下腹肿瘤。在手术中切除的所有标本进行组织病理学诊断,尤其是在基层地区医院,对患者的治疗管理非常重要。