Wangi Harakati, Asdie Rizka Humardewayanti
Department of Internal Medicine, Gatot Subroto Central Army Hospital, Jakarta, Indonesia.
Acta Med Indones. 2009 Jan;41(1):2-5.
To recognize the correlation between lower-extremity functional status and obesity in patients with type-2 DM with PAD complication (with and without peripheral arterial disease).
the study was a cross-sectional study conducted at Outpatients Clinic of Internal Medicine, Dr. Sardjito Central General Hospital in August-December 2006. Fifty-five subjects who were patients with type-2 DM aged more than 50 years agreed to participate and were eligible for the study; while the exclusion criteria included smoking, diabetic ulcer or gangrene, history of amputation due to diabetic ulcer or gangrene. The diagnosis of PAD was based on Ankle Brachial Index < 0.90.
mean age was 62.53 +/- 6.82 years old and mean value of BMI was 24.26 +/- 3.57 kg/m2, 18 subjects (32.7%) were obese. The proportion of obese subjects with PAD was higher compared to the non-obese subjects (41% vs. 27%, p = 0.372). Lower-extremity functional status of type-2 diabetic patients either with or without PAD in obese subjects needs longer period of time (7.17 +/- 1.74 minute and 6.94 +/- 1.48 minute vs. 5.13 +/- 1.47 minute and 4.58 +/- 1.17 minute, p < 0.05 and p < 0.001).
the functional status of lower extremities in obese patients with DM is poorer than the non-obese subjects.
认识2型糖尿病合并PAD并发症（有和无外周动脉疾病）患者的下肢功能状态与肥胖之间的相关性。
本研究为横断面研究，于2006年8月至12月在Sardjito中央总医院内科门诊进行。55名年龄超过50岁的2型糖尿病患者同意参与并符合研究条件；排除标准包括吸烟、糖尿病溃疡或坏疽、因糖尿病溃疡或坏疽导致的截肢史。PAD的诊断基于踝臂指数<0.90。
平均年龄为62.53±6.82岁，BMI平均值为24.26±3.57kg/m²，18名受试者（32.7%）肥胖。肥胖受试者中合并PAD的比例高于非肥胖受试者（41%对27%，p = 0.372）。肥胖受试者中无论有无PAD的2型糖尿病患者的下肢功能状态所需时间更长（7.17±1.74分钟和6.94±1.48分钟对5.13±1.47分钟和4.58±1.17分钟，p<0.05和p<0.001）。
肥胖的糖尿病患者下肢功能状态比非肥胖受试者差。
