Borchard F, Betz P
Center of Pathology, Heinrich-Heine-University of Düsseldorf, Federal Republic of Germany.
Surg Radiol Anat. 1991;13(2):117-21. doi: 10.1007/BF01623884.
For classification of perigastric lymph node metastases in gastric cancer, only topographical aspects are taken into consideration at present. As a numerical classification for lymph node metastases was proposed recently, the current problem is that of determining the number of dissectable perigastric lymph nodes and also assessing the quality of nodal dissection. The perigastric lymph nodes of 10 adults without gastric disease were therefore evaluated microscopically by a serial section technique. On average a total of 36.2 +/- 15.2 perigastric lymph nodes were found, e.g. 14.9 +/- 14.1 lymph nodes on the greater and 7.4 +/- 4.8 on the lesser curvature. These figures are similar to those in fetuses and newborn infants, but they exceed the numbers of perigastric lymph nodes reported in the literature for adults with or without gastric cancer. This difference could be attributable to our use of the serial section technique, because the so-called "micro-lymph nodes" with a diameter of less than 1.5 mm are consequently included in this study. Our results support the assumption, that pathologic processes do not result in any real increase of regional lymph nodes, but in an activation and enlargement of fetal lymph node reserve.
目前，对于胃癌胃周淋巴结转移的分类，仅考虑其局部解剖学特征。由于最近提出了一种淋巴结转移的数值分类方法，当前的问题在于确定可切除的胃周淋巴结数量，并评估淋巴结清扫的质量。因此，我们采用连续切片技术对10例无胃部疾病的成年人的胃周淋巴结进行了显微镜评估。平均共发现36.2±15.2个胃周淋巴结，例如大弯侧有14.9±14.1个，小弯侧有7.4±4.8个。这些数字与胎儿和新生儿的相似，但超过了文献报道的有或无胃癌的成年人的胃周淋巴结数量。这种差异可能归因于我们使用的连续切片技术，因为本研究中纳入了直径小于1.5毫米的所谓“微淋巴结”。我们的结果支持这样一种假设，即病理过程不会导致局部淋巴结真正增加，而是导致胎儿淋巴结储备的激活和增大。
