Li John, De Anindya, Ketchum Kathy, Fagnan L J, Haxby Dean G, Thomas Ann
Divisons of Epidemiology and Community Health, University of Minnesota, USA.
Fam Med. 2009 Mar;41(3):182-7.
Antibiotic resistance is a growing problem that complicates the treatment of various illnesses. This study analyzes Medicaid encounter data to (1) determine antibiotic prescribing rates for common respiratory tract infections in Oregon and (2) assess the effect of receiving an antibiotic at an index visit on whether there was a return visit within 30 days.
Subjects included in this study were Medicaid patients in Oregon between 2001--2003 who were enrolled in Medicaid for a full year and were diagnosed with an upper respiratory tract infection, including bronchitis, sinusitis, acute otitis media (AOM), pharyngitis, and upper respiratory infections (URIs). Claims data were analyzed to determine receipt of an antibiotic within 3 days of the initial visit and if there was a return visit within 30 days.
During 2001--2003, the proportion of patients receiving antibiotics for bronchitis and sinusitis decreased, from 70% to 61%, and from 78% to 74%, respectively, while antibiotic prescribing for AOM, URI, and pharyngitis changed little. After controlling for age, gender, race/ethnicity, Medicaid plan type, and location, we determined that patients who had received antibiotics during the index visit for AOM, URI, and pharyngitis were more likely to return with a respiratory tract infection during the subsequent 30 days than patients who did not receive antibiotics.
Antibiotic prescribing among Medicaid patients in Oregon has decreased. Receiving an antibiotic does not decrease the rate of subsequent return visits.
抗生素耐药性问题日益严重,使各种疾病的治疗变得复杂。本研究分析医疗补助计划的就诊数据,以(1)确定俄勒冈州常见呼吸道感染的抗生素处方率,以及(2)评估在首次就诊时接受抗生素治疗对30天内是否再次就诊的影响。
本研究纳入的受试者为2001年至2003年期间在俄勒冈州参加全年医疗补助计划且被诊断患有上呼吸道感染(包括支气管炎、鼻窦炎、急性中耳炎、咽炎和上呼吸道感染)的医疗补助患者。分析索赔数据,以确定初次就诊后3天内是否接受了抗生素治疗以及30天内是否再次就诊。
在2001年至2003年期间,支气管炎和鼻窦炎患者接受抗生素治疗的比例分别从70%降至61%,从78%降至74%,而急性中耳炎、上呼吸道感染和咽炎的抗生素处方变化不大。在控制了年龄、性别、种族/族裔、医疗补助计划类型和地点后,我们确定,在首次就诊时接受抗生素治疗的急性中耳炎、上呼吸道感染和咽炎患者在随后30天内因呼吸道感染再次就诊的可能性高于未接受抗生素治疗的患者。
俄勒冈州医疗补助患者的抗生素处方率有所下降。接受抗生素治疗并不会降低随后再次就诊的比率。