McLucas Bruce, Yaghmai Babak, Beller Mark
Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Minim Invasive Ther Allied Technol. 2009;18(2):87-92. doi: 10.1080/13645700902719292.
It was the aim of this study to discuss the efficacy of computed tomography angiography after failed uterine artery embolization. We performed a review of cases where embolization of myomata failed to relieve symptoms, or shrink myomata. If MRI showed continued uptake, patients were offered CT angiograms to better direct therapy. Repeat embolization details were compared with findings on CT angiogram. During the study, 675 patients underwent uterine artery embolization. 229 patients underwent follow-up MRI with intravenous contrast, 29 of which showed persistent uptake into myomata. Twelve patients had CT angiogram of the abdomen following MRI and six elected to undergo repeat UAE after CT angiogram. There was a 75% concurrence between CT angiograms and live studies (angiogram during repeat uterine artery embolization). With CTA, five patients showed a unilateral non-uterine blood supply, one showed a bilateral non-gonadal supply to the uterus, and two showed a normal blood supply, with all but two cases confirmed on live angiogram. Based on post-repeat MRI, one of the six repeat UAE patients shows no continued uptake of intravenous contrast to myomata. Four show continued uptake, however, one patient did show decreased size of myomata. CT angiography is a valuable tool to identify collateral and persistent uterine artery supply, and offers great potential for accurate identification and evaluation of extra-gonadal supply to the uterus. It will allow for pre-operative planning, as well as discussion of risks and benefits with patients.
本研究旨在探讨子宫动脉栓塞失败后计算机断层血管造影(CTA)的疗效。我们回顾了肌瘤栓塞未能缓解症状或缩小肌瘤的病例。如果磁共振成像(MRI)显示持续摄取,会为患者提供CT血管造影以更好地指导治疗。将重复栓塞的细节与CT血管造影的结果进行比较。在研究期间,675例患者接受了子宫动脉栓塞术。229例患者接受了静脉注射造影剂的随访MRI检查,其中29例显示肌瘤持续摄取造影剂。12例患者在MRI检查后接受了腹部CT血管造影,其中6例在CT血管造影后选择接受重复子宫动脉栓塞术(UAE)。CT血管造影与实时研究(重复子宫动脉栓塞术中的血管造影)之间的一致性为75%。通过CTA,5例患者显示单侧非子宫供血,1例显示双侧非性腺供血至子宫,2例显示正常供血,除2例病例外,所有病例均在实时血管造影中得到证实。根据重复MRI检查,6例重复UAE患者中有1例显示肌瘤未持续摄取静脉造影剂。4例显示持续摄取,然而,1例患者肌瘤大小确实有所减小。CT血管造影是识别子宫动脉侧支和持续供血的重要工具,在准确识别和评估子宫性腺外供血方面具有巨大潜力。它将有助于术前规划,并与患者讨论风险和益处。