Makino Michiko, Masaki Chihiro, Tomoeda Kei, Kharouf Elyes, Nakamoto Tetsuji, Hosokawa Ryuji
Department of Oral Reconstruction and Rehabilitation, Kyushu Dental College, Graduate School, Fukuoka, Japan.
Int J Prosthodont. 2009 Jan-Feb;22(1):43-8.
Bruxism and parafunctions are potential risk factors for implant and prosthodontic treatment failure. However, the etiology of bruxism remains unknown. This study sought to clarify the relationship between bruxism behavior and a salivary stress biomarker level.
Forty-six volunteers (23 men, 23 women) participated in this study. Bruxism behavior was assessed using a self-administered questionnaire, study casts, and BiteStrip, a miniature electronic screener used to detect sleep bruxism. The questionnaire consisted of six items asking about bruxism, occlusion, jaw functional limitation, and dentition. Occlusal wear was assessed from dental casts and calculated as the sum of the facets in the maxillary arch segment. Participants used BiteStrip at home for one night and the score was evaluated. Two-minute stimulated whole saliva samples were collected from participants to measure daytime levels of chromogranin A (CgA), a major salivary stress biomarker. Nonparametric tests of the relationship between variables were performed using the Spearman R and Kendall tau statistical correlation tests.
There was a positive correlation between self-reported bruxism and self-reported jaw functional limitation. Occlusal wear did not significantly correlate with occlusion, jaw functional limitation, or dentition, but it did significantly correlate with self-reported bruxism behavior, as well as the BiteStrip score. It was interesting to find that the CgA level was significantly negative in correlation with the BiteStrip score.
Sleep bruxism is believed to be a stress-related sleep disorder. The results suggest that daytime psychological stress level is significantly negative in correlation with sleep bruxism behavior.
磨牙症和副功能是种植治疗及修复治疗失败的潜在风险因素。然而，磨牙症的病因尚不清楚。本研究旨在阐明磨牙症行为与唾液应激生物标志物水平之间的关系。
46名志愿者（23名男性，23名女性）参与了本研究。使用一份自填式问卷、研究模型以及用于检测睡眠磨牙症的微型电子筛查器BiteStrip对磨牙症行为进行评估。问卷包含六个项目，询问有关磨牙症、咬合、颌功能受限及牙列情况。根据牙模评估咬合磨损情况，并计算上颌牙弓段小平面的总和。参与者在家中使用BiteStrip一晚，并对得分进行评估。采集参与者两分钟的刺激性全唾液样本，以测量主要唾液应激生物标志物嗜铬粒蛋白A（CgA）的日间水平。使用Spearman R和Kendall tau统计相关性检验对变量之间的关系进行非参数检验。
自我报告的磨牙症与自我报告的颌功能受限之间存在正相关。咬合磨损与咬合、颌功能受限或牙列情况无显著相关性，但与自我报告的磨牙症行为以及BiteStrip得分显著相关。有趣的是，发现CgA水平与BiteStrip得分呈显著负相关。
睡眠磨牙症被认为是一种与压力相关的睡眠障碍。结果表明，日间心理压力水平与睡眠磨牙症行为呈显著负相关。
