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针对门静脉闭塞且存在巨大自发性脾肾分流的患者,活体供肝移植中肾门静脉吻合术的技术改良

Technical modification of reno-portal anastomosis in living donor liver transplantation for patients with obliterated portal vein and large spontaneous splenorenal shunts.

作者信息

Moon Deok-Bog, Lee Sung-Gyu, Ahn Chul-Soo, Kim Ki-Hun, Hwang Shin, Ha Tae-Yong, Song Gi-Won, Jung Dong-Hwan, Ryu Je-Ho, Kim Kwan-Woo, Choi Nam-Kyu, Ko GiYoung, Sung KyuBo, Lee SungKoo

机构信息

Division of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

出版信息

Hepatogastroenterology. 2008 Nov-Dec;55(88):2193-9.

PMID:19260504
Abstract

BACKGROUND/AIMS: End-stage liver disease patients with obliterated portal vein(PV) and large spontaneous splenorenal shunts (SRS) are often indicated to renoportal bypass as a reconstruction of portal inflow during liver transplantation. The aim of this study was to show the feasibility and safety of the side-to-end (S-to-E) renoportal anastomosis (RP-A).

METHODOLOGY

RP-A were performed in 5 patients among 597 adult living donor liver transplantation (LDLT) with end-to-end (E-to-E) or S-to-E method interposing cadaveric fresh vessel grafts between left renal vein (LRV) and PV of liver graft from October 2005 to June 2008.

RESULTS

One patient underwent E-to-E RP-A, but it was technically difficult in our experience because of thin and retracted renal vein end under poor operation field. Remaining four patients underwent side-to-end (S-to-E) RP-A which allowed us to perform easy and secure anastomosis under better and more stable operation field, because LRV continuity with vena cava was preserved without retraction of anastomosis site. Except one patient having two left-lobes dual-graft LDLT who died from cerebral hemorrhage, four patients were recovered well with normal graft function and a patent RP-A.

CONCLUSIONS

S-to-E anastomosis is technically more feasible and easier method than E-to-E anastomosis for RP-A interposing cadaveric fresh vessel in LDLT.

摘要

背景/目的:门静脉闭塞且存在巨大自发性脾肾分流的终末期肝病患者,在肝移植期间常需进行肾门静脉搭桥以重建门静脉血流。本研究旨在展示端侧肾门静脉吻合术(RP - A)的可行性和安全性。

方法

2005年10月至2008年6月,在597例成人活体肝移植(LDLT)中,5例患者采用端端(E - to - E)或端侧(S - to - E)方法进行RP - A,在左肾静脉(LRV)与肝移植的门静脉之间植入尸体新鲜血管移植物。

结果

1例患者接受了E - to - E RP - A,但根据我们的经验,由于手术视野不佳导致肾静脉末端纤细且回缩,该操作在技术上存在困难。其余4例患者接受了端侧(S - to - E)RP - A,这使我们能够在更好、更稳定的手术视野下轻松且安全地进行吻合,因为保留了LRV与腔静脉的连续性,吻合部位无回缩。除1例接受双左叶双移植物LDLT的患者死于脑出血外,其余4例患者恢复良好,移植肝功能正常,RP - A通畅。

结论

在LDLT中,对于植入尸体新鲜血管的RP - A,端侧吻合术在技术上比端端吻合术更可行、更简便。

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