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有童年性虐待史的HIV阳性成年人的医疗治疗利用情况及对抗逆转录病毒疗法的依从性。

Utilization of medical treatments and adherence to antiretroviral therapy among HIV-positive adults with histories of childhood sexual abuse.

作者信息

Meade Christina S, Hansen Nathan B, Kochman Arlene, Sikkema Kathleen J

机构信息

McLean Hospital/Harvard Medical School, Belmont, Massachusetts, USA.

出版信息

AIDS Patient Care STDS. 2009 Apr;23(4):259-66. doi: 10.1089/apc.2008.0210.

Abstract

HIV is a chronic, life-threatening illness that necessitates regular and consistent medical care. Childhood sexual abuse (CSA) is a common experience among HIV-positive adults and may interfere with treatment utilization. This study examined rates and correlates of treatment utilization among HIV-positive adults with CSA enrolled in a coping intervention trial in New York City. The baseline assessment included measures of treatment utilization, mental health, substance abuse, and other psychosocial factors. In 2002-2004, participants (50% female, 69% African-American, M = 42.3 +/- 6.8 years old) were recruited. Nearly all (99%) received HIV medical care. However, 20% had no outpatient visits and 24% sought emergency services in the past 4 months. Among 184 participants receiving antiretroviral therapy (ART), 22% were less than 90% adherent in the past week. In a multivariable logistic regression model, no outpatient treatment was associated with African American race (AOR = 3.46 [1.42-8.40]), poor social support (AOR = 1.59 [1.03-2.45]), and abstinence from illicit drug use (AOR = 0.37 [0.16-0.85]). Emergency service utilization was associated with HIV symptoms (AOR = 2.30 [1.22-4.35]), binge drinking (AOR=2.92 (1.18-7.24)), and illicit drug use (AOR = 1.98 [1.02-3.85]). Poor medication adherence was associated with trauma symptoms (AOR = 2.64 [1.07-6.75]) and poor social support (AOR = 1.82 [1.09-2.97]). In sum, while participants had access to HIV medical care, a sizable minority did not adhere to recommended guidelines and thus may not be benefiting optimally from treatment. Interventions targeting HIV-positive adults with CSA histories may need to address trauma symptoms, substance abuse, and poor social support that interfere with medical treatment utilization and adherence.

摘要

人类免疫缺陷病毒(HIV)是一种慢性、危及生命的疾病,需要定期持续的医疗护理。儿童期性虐待(CSA)在HIV阳性成年人中很常见,可能会影响治疗的利用。本研究调查了参与纽约市一项应对干预试验的有儿童期性虐待史的HIV阳性成年人的治疗利用率及其相关因素。基线评估包括治疗利用、心理健康、药物滥用和其他社会心理因素的测量。在2002年至2004年期间,招募了参与者(50%为女性,69%为非裔美国人,平均年龄42.3±6.8岁)。几乎所有参与者(99%)都接受了HIV医疗护理。然而,20%的人在过去4个月中没有门诊就诊,24%的人寻求过急诊服务。在184名接受抗逆转录病毒治疗(ART)的参与者中,22%在过去一周的依从性低于90%。在多变量逻辑回归模型中,未接受门诊治疗与非裔美国人种族(调整后比值比[AOR]=3.46[1.42 - 8.40])、社会支持差(AOR = 1.59[1.03 - 2.45])以及不使用非法药物(AOR = 0.37[0.16 - 0.85])有关。急诊服务利用与HIV症状(AOR = 2.30[1.22 - 4.35])、暴饮(AOR = 2.92[1.18 - 7.24])和使用非法药物(AOR = 1.98[1.02 - 3.85])有关。药物依从性差与创伤症状(AOR = 2.64[1.07 - 6.75])和社会支持差(AOR = 1.82[1.09 - 2.97])有关。总之,虽然参与者能够获得HIV医疗护理,但仍有相当一部分少数人未遵循推荐的指导方针,因此可能无法从治疗中获得最佳益处。针对有儿童期性虐待史的HIV阳性成年人的干预措施可能需要解决影响医疗治疗利用和依从性的创伤症状、药物滥用和社会支持差等问题。

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Childhood abuse and initial presentation for HIV care: an opportunity for early intervention.
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