急性泛发性脓疱性皮病：12例报告及文献复习
Acute generalized exanthematous pustulosis: report of 12 cases and literature review.
作者信息
Guevara-Gutierrez Elizabeth, Uribe-Jimenez Elia, Diaz-Canchola Margarita, Tlacuilo-Parra Alberto
机构信息
Instituto Dermatológico de Jalisco, Secretaría de Salud Jalisco, Guadalajara, Jalisco, Mexico.
出版信息
Int J Dermatol. 2009 Mar;48(3):253-8. doi: 10.1111/j.1365-4632.2009.03908.x.
BACKGROUND
Acute generalized exanthematous pustulosis is an acute pustular eruption occurring after infection and/or drug ingestion, with spontaneous cure after a single eruption.
AIM
To communicate a series of cases of acute generalized exanthematous pustulosis.
METHODS
A retrospective analysis was performed on cases of acute generalized exanthematous pustulosis, observed between 1993 and 2006 at the Dermatology Department, Hospital General de Occidente, Jalisco, Mexico.
RESULTS
Twelve patients were included, with a predominance of male patients and a mean age of 28 years. The most common cause was drugs, detected in 83% of cases, and most of these were a result of anticonvulsants and antimicobials. The most frequent symptoms were itching, present in all cases, and fever, present in 92% of cases.
CONCLUSIONS
Acute generalized exanthematous pustulosis is considered to be a distinct clinical and histopathologic entity. Because of its self-resolving character, early recognition can help to avoid unnecessary diagnostic studies and treatments.
背景
急性泛发性脓疱病是一种在感染和/或药物摄入后发生的急性脓疱性皮疹，单次发作后可自愈。
目的
报告一系列急性泛发性脓疱病病例。
方法
对1993年至2006年期间在墨西哥哈利斯科州西总医院皮肤科观察到的急性泛发性脓疱病病例进行回顾性分析。
结果
纳入12例患者，以男性患者为主，平均年龄28岁。最常见的病因是药物，在83%的病例中检测到，其中大多数是抗惊厥药和抗菌药所致。最常见的症状是瘙痒，所有病例均有，发热见于92%的病例。
结论
急性泛发性脓疱病被认为是一种独特的临床和组织病理学实体。由于其自限性，早期识别有助于避免不必要的诊断检查和治疗。
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