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前路颈椎间盘切除钛质椎间融合器融合术后的长期疗效及相邻椎间盘退变情况

Long term outcome and adjacent disc degeneration after anterior cervical discectomy and fusion with titanium cylindrical cages.

作者信息

Sugawara Taku, Itoh Yasunobu, Hirano Yoshitaka, Higashiyama Naoki, Mizoi Kazuo

机构信息

Department of Neurosurgery, School of Medicine, Akita University, Akita, Japan.

出版信息

Acta Neurochir (Wien). 2009 Apr;151(4):303-9; discussion 309. doi: 10.1007/s00701-009-0217-5. Epub 2009 Mar 5.

Abstract

BACKGROUND

Anterior cervical discectomy and fusion (ACDF) is widely performed for the treatment of cervical spinal degenerative disease. Autogenic or allogenic bone grafts are used for interbody fusion with satisfactory long term outcomes. However, harvest of the autograft causes donor site complications and allograft is associated with low fusion rate. Threaded titanium cages (TC) have recently been introduced to cope with these disadvantages, but there is little evidence of long term results.

METHODS

The long term outcome was studied after ACDF using TC. Clinical and imaging follow up was performed in 41 patients for at least 5 years (range 5-8.3 years). New computer-assisted measurement methods for radiographs are proposed.

FINDINGS

ACDF with TC achieved 80% excellent or good outcome by Odom's criteria, 95% fusion rate, and few minor complications. Asymptomatic adjacent disc degeneration was detected in 50% of the patients by our measurement methods. However, symptomatic adjacent disc degeneration occurred in 5% of the patients and only 2% required additional surgery.

CONCLUSIONS

These results are comparable or better than those after ACDF with autograft or allograft. ACDF with TC can achieve rigid fixation and provide good long term results.

摘要

背景

颈椎前路椎间盘切除融合术(ACDF)广泛应用于治疗颈椎退行性疾病。自体或异体骨移植用于椎间融合,长期效果良好。然而,自体骨移植会导致供体部位并发症,而异体骨移植则与融合率低有关。带螺纹钛笼(TC)最近被引入以应对这些缺点,但长期结果的证据很少。

方法

对使用TC进行ACDF后的长期结果进行了研究。对41例患者进行了至少5年(5 - 8.3年)的临床和影像学随访。提出了用于X线片的新的计算机辅助测量方法。

结果

根据奥多姆标准,使用TC的ACDF取得了80%的优良结果、95%的融合率,且并发症较少。通过我们的测量方法,50%的患者检测到无症状的相邻椎间盘退变。然而,5%的患者出现了有症状的相邻椎间盘退变,只有2%的患者需要额外手术。

结论

这些结果与使用自体骨或异体骨进行ACDF后的结果相当或更好。使用TC的ACDF可以实现坚固固定并提供良好的长期效果。

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