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杓状软骨内收并喉内移成形术与注射或喉内移成形术对比:杓状软骨固定术的作用

Arytenoid adduction with medialization laryngoplasty versus injection or medialization laryngoplasty: the role of the arytenoidopexy.

作者信息

Mortensen Melissa, Carroll Linda, Woo Peak

机构信息

Department of Otolaryngology-Head and Neck Surgery, University of Virginia, Charlottesville, Virginia, USA.

出版信息

Laryngoscope. 2009 Apr;119(4):827-31. doi: 10.1002/lary.20171.

Abstract

OBJECTIVES/HYPOTHESIS: There continues to be controversy about the added role of arytenoid adduction (AA) in the rehabilitation of unilateral vocal cord paralysis (UVCP). Some authors feel that the added morbidity of AA is not warranted in UVCP rehabilitation. Objective analysis of acoustic and aerodynamic measures were performed before and after surgery to try to resolve this controversy.

METHODS

This is an institutional review board-approved retrospective study of 85 patients with UVCP undergoing surgical rehabilitation by injection laryngoplasty (n = 45), medialization laryngoplasty (n = 14), or medialization laryngoplasty with arytenoid adduction (n = 26). Acoustic and aerodynamic parameters were studied before and after surgery. The medialization laryngoplasty (ML) group (medialization alone, injection laryngoplasty ML/IL) data were compared to the AA-ML group using a paired t test for the individual measures and analysis of variance (ANOVA) for the multivariate analysis of acoustic and aerodynamic measures.

RESULTS

In all treatment arms there were statistically significant improvements in all acoustic and aerodynamic measures after intervention (P < .05). For ML and IL, the mean difference between preoperative from postoperative jitter was 1.504%, shimmer 3.265%, noise to harmonic ratio (NHR) 0.036, mean phonation time 4.523 seconds, transglottic flow 0.130 L/s, and subglottic pressure 0.616 cm H2O. For AA-ML the mean difference between preoperative and postoperative jitter was 2.431%, shimmer 6.068%, NHR 0.082, mean phonation time 6.74 seconds, flow 0.181 L/s, and subglottic pressure 0.611 cm H2. Preoperatively, the average phonatory function of the AA-ML group was worse than the ML group. Comparison between the two treatment arms, individual acoustic and aerodynamic measures, were not different (paired t test, P < .05). However, mulitvariate analysis (ANOVA, P < .05) of acoustic and aerodynamic measures, showed a statistically significant difference between the two groups. The degree of change was significantly better in the AA-ML group.

CONCLUSIONS

AA-ML and IL/ML improve phonatory function, but not to normal. We were unable to demonstrate a statistical difference between groups using a single measure, but using mutlivariate analysis, there is a statistical significance between the groups. AA-ML patients had worse preoperative function and had better postoperative function. When clinically indicated, AA-ML procedure does appear to correct the physiology of the incompetent larynx better than ML alone.

摘要

目的/假设:在单侧声带麻痹(UVCP)的康复治疗中,杓状软骨内收术(AA)的附加作用一直存在争议。一些作者认为,在UVCP康复治疗中,AA增加的发病率是不必要的。为解决这一争议,我们在手术前后对声学和空气动力学指标进行了客观分析。

方法

这是一项经机构审查委员会批准的回顾性研究,对85例接受手术康复治疗的UVCP患者进行了研究,其中45例行注射喉成形术,14例行喉内移术,26例行杓状软骨内收喉内移术。在手术前后对声学和空气动力学参数进行了研究。使用配对t检验对个体测量指标进行分析,并使用方差分析(ANOVA)对声学和空气动力学指标进行多变量分析,将喉内移术组(单纯喉内移术、注射喉成形术喉内移术/IL)的数据与AA-喉内移术组进行比较。

结果

在所有治疗组中,干预后所有声学和空气动力学指标均有统计学意义的改善(P < .05)。对于喉内移术和注射喉成形术,术前与术后的抖动平均差异为1.504%,闪烁为3.265%,噪声谐波比(NHR)为0.036,平均发声时间为4.523秒,声门间流量为0.130 L/s,声门下压力为0.616 cm H2O。对于AA-喉内移术组,术前与术后的抖动平均差异为2.431%,闪烁为6.068%,NHR为0.082,平均发声时间为6.74秒,流量为0.181 L/s,声门下压力为0.611 cm H2。术前,AA-喉内移术组的平均发声功能比喉内移术组差。两组治疗组之间的个体声学和空气动力学测量指标没有差异(配对t检验,P < .05)。然而,声学和空气动力学指标的多变量分析(ANOVA,P < .05)显示两组之间存在统计学意义的差异。AA-喉内移术组的变化程度明显更好。

结论

AA-喉内移术和IL/喉内移术可改善发声功能,但未恢复至正常水平。我们无法通过单一测量指标证明两组之间存在统计学差异,但使用多变量分析时,两组之间存在统计学意义。AA-喉内移术组患者术前功能较差,术后功能较好。在临床有指征时,AA-喉内移术似乎比单纯喉内移术能更好地纠正喉功能不全的生理状态。

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