Foresti Elisabetta, Fornero Elisa, Lesci Isidoro Giorgio, Rinaudo Caterina, Zuccheri Tommaso, Roveri Norberto
Department of Chemistry, University of Bologna, Via Selmi 2, Bologna, Italy.
J Hazard Mater. 2009 Aug 15;167(1-3):1070-9. doi: 10.1016/j.jhazmat.2009.01.103. Epub 2009 Feb 6.
The chrysotile fibres toxicity appears correlated to the redox activity of iron present in the chrysotile structure. In fact the generation of reactive oxygen species and other radicals appears catalyzed by iron ions and closely related to Fe ions organization in specific crystallographic sites having a capability to activate free radical generation. The Fe substitution to Mg and/or Si in the chrysotile structure appears important for asbestos health hazard investigation. Infrared and Raman spectroscopic analyses have been utilized to investigate Mg and/or Si ions replacement by Fe ions in chrysotile structure as a function of the Fe doping extent. Geoinspired synthetic chrysotile at different Fe doping extents has been obtained as unique phase by hydrothermal reaction in the presence or not of metallic Fe in the synthetic environment. The results highlight that Fe can replace both Mg and Si, differently modifying the chrysotile structure as a function of the Fe doping extent and the Fe doping process. The contemporary iron substitution into the octahedral and tetrahedral sheets reveals an appreciable increase of the dehydroxylation temperature which occurs at higher temperature than for iron-free sample. The results highlight the role of Fe substitution in the asbestos structure influencing the health hazard of biological systems.
温石棉纤维的毒性似乎与温石棉结构中存在的铁的氧化还原活性相关。事实上，活性氧物种和其他自由基的产生似乎由铁离子催化，并且与铁离子在特定晶体学位置的组织密切相关，这些位置具有激活自由基产生的能力。温石棉结构中镁和/或硅被铁取代，这对石棉健康危害调查似乎很重要。红外光谱和拉曼光谱分析已被用于研究温石棉结构中铁离子取代镁和/或硅离子的情况，作为铁掺杂程度的函数。通过在合成环境中存在或不存在金属铁的情况下进行水热反应，已获得不同铁掺杂程度的受地质启发合成温石棉作为唯一相。结果表明，铁可以取代镁和硅，根据铁掺杂程度和铁掺杂过程不同地改变温石棉结构。八面体和四面体片中同时进行的铁取代显示脱羟基温度明显升高，该温度比无铁样品的脱羟基温度更高。结果突出了铁取代在石棉结构中对生物系统健康危害的影响作用。
