Cashen Katherine, Kamat Deepak
Carman and Adams Department of Pediatrics, Children's Hospital of Michigan, Detroit, Michigan, USA.
Clin Pediatr (Phila). 2009 Jul;48(6):679-82. doi: 10.1177/0009922809333090. Epub 2009 Mar 4.
Periodic fever is uncommon in children. The differential diagnosis is large, even though associated symptoms such as rash may help narrow the differential diagnosis. Atypical presentations require thoughtful evaluation. This article describes a case of a 4-year-old boy who presented to the emergency department with recurrent fever, vomiting, abdominal pain, myalgias, and rash. His hospital course is described along with a review on the background, evaluation, management, and complications of tumor necrosis receptor-1 alpha periodic syndrome.
周期性发热在儿童中并不常见。鉴别诊断范围很广，尽管皮疹等相关症状可能有助于缩小鉴别诊断范围。非典型表现需要进行深入评估。本文描述了一名4岁男孩的病例，他因反复发热、呕吐、腹痛、肌痛和皮疹就诊于急诊科。文中介绍了他的住院病程，并对肿瘤坏死因子受体1α周期性综合征的背景、评估、管理及并发症进行了综述。
