Nielsen Finn Cilius, Borregaard Niels
Haematologisk Afdeling, Rigshospitalet, DK-2100 København Ø.
Ugeskr Laeger. 2009 Mar 2;171(10):790-4.
Pharmacogenetics traditionally designates the study of genetically determined variation in metabolism of drugs and toxins from the environment. The concept of phamacogenetics has been widened to encompass how essential genetic alterations central to the development of diseases may by used to target medical treatment in a patient-tailored way. This paper highlights some of the novel developments in relation to oncology and haematology.
传统上，药物遗传学指对由基因决定的药物及环境毒素代谢差异的研究。药物遗传学的概念已得到拓展，涵盖了如何利用对疾病发生至关重要的基因改变，以患者个体化的方式进行靶向治疗。本文重点介绍了肿瘤学和血液学方面的一些新进展。
