Bonham Vence L, Sellers Sherrill L, Gallagher Thomas H, Frank Danielle, Odunlami Adebola O, Price Eboni G, Cooper Lisa A
Social and Behavioral Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
Genet Med. 2009 Apr;11(4):279-86. doi: 10.1097/GIM.0b013e318195aaf4.
This qualitative study explored black and white general internists' attitudes about the relevance of race in clinical care; views of the relationships among race, genetics, and disease; and expectations about the future of genetics and health.
We conducted 10 racially concordant focus groups of primary care physicians in five metropolitan areas in the United States. Ninety board certified or eligible general internists (50 self-identified whites and 40 self-identified blacks) participated in the study. Analysis included a two-stage independent review and adjudication process.
Both black and white physicians concluded that the race of the patient is medically relevant but did not agree upon why race is important in clinical decisions. They were reticent to make connections among race, genetics, and disease and asserted that genetics has a limited role in explaining racial differences in health. However, they were enthusiastic about the future of genomic medicine, believing that the main benefit will be the potential to improve the efficacy of commonly used drugs.
Understanding the similarities and differences between black and white physicians' attitudes and beliefs about race, health and genetics is important for the translation of genomics to clinical care.
本定性研究探讨了黑人和白人普通内科医生对种族在临床护理中的相关性的态度;对种族、遗传学和疾病之间关系的看法;以及对遗传学和健康未来的期望。
我们在美国五个大都市地区对基层医疗医生进行了10个种族匹配的焦点小组访谈。90名获得委员会认证或符合条件的普通内科医生(50名自我认定为白人,40名自我认定为黑人)参与了该研究。分析包括两阶段的独立审查和裁决过程。
黑人和白人医生都得出结论,患者的种族在医学上具有相关性,但对于种族在临床决策中为何重要并未达成一致。他们不愿在种族、遗传学和疾病之间建立联系,并声称遗传学在解释健康方面的种族差异方面作用有限。然而,他们对基因组医学的未来充满热情,认为其主要益处将是提高常用药物疗效的潜力。
了解黑人和白人医生在种族、健康和遗传学方面的态度和信念的异同,对于将基因组学转化为临床护理至关重要。