1型糖尿病自然病程中的C肽。
C-peptide in the natural history of type 1 diabetes.
作者信息
Palmer Jerry P
机构信息
Department of Medicine, Veterans Affairs Puget Sound Health Care System and University of Washington, Seattle, WA, USA.
出版信息
Diabetes Metab Res Rev. 2009 May;25(4):325-8. doi: 10.1002/dmrr.943.
Abstract
Type 1 diabetes is diagnosed when the patient's endogenous insulin secretion decreases to a level which results in hyperglycemia. After diagnosis, insulin secretion continues to decline. As a reference for clinical trials trying to preserve endogenous beta-cell function in patients with recently diagnosed type 1 diabetes, in this short review I attempt to summarize the natural history of endogenous beta-cell function after the diagnosis of type 1 diabetes.
摘要
当患者内源性胰岛素分泌降至导致高血糖的水平时，即可诊断为1型糖尿病。诊断后，胰岛素分泌会持续下降。作为试图在新诊断的1型糖尿病患者中保留内源性β细胞功能的临床试验的参考，在这篇简短的综述中，我试图总结1型糖尿病诊断后内源性β细胞功能的自然病程。
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