Katsarava Zaza, Holle Dagny, Diener Hans-Christoph
Department of Neurology, University of Duisburg-Essen, Hufelandstrasse 55, Essen, Germany.
Curr Neurol Neurosci Rep. 2009 Mar;9(2):115-9. doi: 10.1007/s11910-009-0019-4.
The term medication overuse headache (MOH) was recently introduced by the International Headache Society to describe daily or nearly daily (chronic) headache that occurs after the regular intake (overuse) of any kind of antiheadache or antimigraine drug. Chronic headache is a growing problem throughout the world. It affects up to 3% to 4% of the general population, and 30% to 50% of such headaches are attributed to overuse of antiheadache drugs. This article reviews the literature on the epidemiology, risk factors, and pathophysiology of MOH. It also summarizes current strategies for treating and preventing headache chronicity.
“药物过度使用性头痛（MOH）”这一术语最近由国际头痛协会提出，用于描述在常规摄入（过度使用）任何种类的抗头痛或抗偏头痛药物后出现的每日或几乎每日（慢性）头痛。慢性头痛在全球范围内是一个日益严重的问题。它影响着高达3%至4%的普通人群，其中30%至50%的此类头痛归因于抗头痛药物的过度使用。本文综述了关于药物过度使用性头痛的流行病学、危险因素和病理生理学的文献。它还总结了目前治疗和预防头痛慢性化的策略。
