[肺的脂肪生成酶与年龄的关系]

[Lipogenic enzymes of the lung in relation to age].

作者信息

Rassoul F, Richter V, Morwinski I, Rotzsch W

机构信息

Institut für Klinische Chemie und Laboratoriumsdiagnostik, Bereich Medizin der Universität Leipzig.

出版信息

Z Gerontol. 1991 May-Jun;24(3):118-20.

PMID:1926999

Abstract

The activities of lipogenic enzymes of the lung of female rats of the Wistar strain were measured in the age groups 3, 18, 21, 25, and 30 months. The activities of malic enzyme (EC. 1.1.1.40) and citrate cleavage enzyme (EC. 4.1.3.8) decrease in dependence on aging. In contrast, the enzymes of pentose phosphate shuttle glucose-6-phosphate dehydrogenase (EC. 1.1.1.49) and 6-phosphogluconate dehydrogenase (EC. 1.1.1.44) do not show an age dependence.

摘要

在3、18、21、25和30月龄的年龄组中，测定了Wistar品系雌性大鼠肺中脂肪生成酶的活性。苹果酸酶（EC. 1.1.1.40）和柠檬酸裂解酶（EC. 4.1.3.8）的活性随年龄增长而降低。相比之下，磷酸戊糖途径的葡萄糖-6-磷酸脱氢酶（EC. 1.1.1.49）和6-磷酸葡萄糖酸脱氢酶（EC. 1.1.1.44）的活性不显示年龄依赖性。