Zarrouf Fahd, Griffith James, Jesse Jane
Medicine-Psychiatry Residency, WVU, Charleston, WV, USA.
W V Med J. 2009 Mar-Apr;105(2):22, 24-6.
Normal Pressure Hydrocephalus (NPH) is a very rare and reversible cause of dementia, and it is often misdiagnosed as other, more common types of cognitive impairments. The classical triad of NPH includes: gait disturbances, urinary incontinence, and cognitive dysfunction. There is a wide spectrum of psychiatric symptoms that may precede or combine the triad NPH symptoms. In this paper, we report a case of 78-year-old NPH patient with puzzling presentation and his cognitive symptoms' response to ventriculoperitoneal shunt. A review of the literature about NPH pathophysiology, evaluation, its association with several psychiatric and cognitive symptoms, available treatment outlines, and suggested future research directions were evaluated.
正常压力脑积水(NPH)是一种非常罕见且可逆转的痴呆病因,常被误诊为其他更常见的认知障碍类型。NPH的典型三联征包括:步态障碍、尿失禁和认知功能障碍。在NPH症状三联征之前或与之并存的还有各种各样的精神症状。本文报告了一例78岁表现令人困惑的NPH患者及其认知症状对脑室腹腔分流术的反应。对有关NPH病理生理学、评估、其与多种精神和认知症状的关联、现有治疗概述以及未来研究方向建议的文献进行了评估。