Benejam B, Poca M A, Junqué C, Solana E, Sahuquillo J
Unidad de Investigación de Neurotraumatología-Neurocirugía, Institut de Recerca Vall d'Hebron, Barcelona.
Neurocirugia (Astur). 2008 Aug;19(4):309-21.
Normal pressure hydrocephalus (NPH) is characterized by gait disturbance, urinary incontinence and dementia, and is associated with variable ventricular enlargement. The most accepted treatment of NPH is the placement of a cerebrospinal fluid shunt. Owing to the characteristics of the patients and the invasive nature of the surgical treatment, it is fundamental to detect those patients who could obtain a greater benefit from the treatment. Neuropsychological assessment of these patients could significantly contribute to a better diagnosis of NPH, determining a cognitive deterioration profile for these patients, allowing the assessment of treatment efficacy and helping to detect other additional causes of dementia. The aim of this study is to describe the cognitive deterioration profile of NPH patients and to present the clinical, functional and neuropsychological assessment protocol used in our hospital.
正常压力脑积水（NPH）的特征为步态障碍、尿失禁和痴呆，并伴有不同程度的脑室扩大。NPH最常用的治疗方法是放置脑脊液分流管。鉴于患者的特点以及手术治疗的侵入性，识别那些能从治疗中获得更大益处的患者至关重要。对这些患者进行神经心理学评估有助于更好地诊断NPH，确定这些患者的认知衰退模式，评估治疗效果并有助于发现痴呆的其他潜在病因。本研究旨在描述NPH患者的认知衰退模式，并介绍我院使用的临床、功能和神经心理学评估方案。
