Almeida Filho Dilermando Pereira de, Oliveira Laerte Justino de, Amaral Vivian Ferreira do
Center for Health and Biological Sciences, Pontifícia Universidade Católica do Paraná, Curitiba, Paraná, Brazil.
Sao Paulo Med J. 2008 Nov;126(6):305-8. doi: 10.1590/s1516-31802008000600002.
Diagnoses of endometriosis are based on observation of endometriotic lesions by means of laparoscopy, along with the pathological findings. The aim of this study was to evaluate the sensitivity and specificity of the macroscopic findings in relation to the histopathological findings. More specifically, we aimed to test the efficacy of laparoscopy alone for diagnosing endometriosis and to evaluate the laterality of endometriosis among the study population.
Cross-sectional study on women undergoing laparoscopy due to pelvic pain or infertility, in the Gynecology Department of Hospital Santa Cruz in Curitiba, Paraná, Brazil, and Pontifícia Universidade Católica do Paraná.
A total of 976 patients underwent laparoscopy and biopsy due to pelvic pain and/or infertility. We analyzed the laparoscopic and histopathological findings from patients with pelvic endometriosis (n = 468) and patients without endometriosis (n = 508).
In 468 (47.95%) of the cases, the clinical and laparoscopic findings were consistent with endometriosis, and this was confirmed histopathologically in 337 (34.5%). Among the remaining 508 patients, although the laparoscopy was performed for other reasons relating to acute pelvic pain, eight were diagnosed with endometriosis from histopathological examination of the pelvic specimens obtained. Therefore, endometriosis was confirmed in 345 patients (35.3%). In comparison with the histopathology, laparoscopy alone presented 97.68% sensitivity, 79.23% specificity, 72% positive predictive value and 98.42% negative predictive value.
Laparoscopy should be used in conjunction with histopathology for diagnosing endometriosis.
子宫内膜异位症的诊断基于通过腹腔镜观察子宫内膜异位病变以及病理检查结果。本研究的目的是评估宏观检查结果相对于组织病理学检查结果的敏感性和特异性。更具体地说,我们旨在测试单纯腹腔镜检查诊断子宫内膜异位症的有效性,并评估研究人群中子宫内膜异位症的左右侧情况。
在巴西巴拉那州库里蒂巴市圣克鲁斯医院妇产科以及巴拉那天主教大学,对因盆腔疼痛或不孕接受腹腔镜检查的女性进行横断面研究。
共有976例患者因盆腔疼痛和/或不孕接受了腹腔镜检查和活检。我们分析了盆腔子宫内膜异位症患者(n = 468)和无子宫内膜异位症患者(n = 508)的腹腔镜检查和组织病理学检查结果。
在468例(47.95%)病例中,临床和腹腔镜检查结果与子宫内膜异位症相符,其中337例(34.5%)经组织病理学证实。在其余508例患者中,尽管腹腔镜检查是因与急性盆腔疼痛相关的其他原因进行的,但从所获取的盆腔标本的组织病理学检查中发现有8例被诊断为子宫内膜异位症。因此,345例患者(占35.3%)被确诊为子宫内膜异位症。与组织病理学相比,单纯腹腔镜检查的敏感性为97.68%,特异性为79.23%,阳性预测值为72%,阴性预测值为98.42%。
诊断子宫内膜异位症时,腹腔镜检查应与组织病理学检查结合使用。