Limaye Sameer, Cooper Jonathan
Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Age Ageing. 2009 Jul;38(4):483-4. doi: 10.1093/ageing/afp026. Epub 2009 Mar 9.
Reversible Posterior Leukoencephalopathy Syndrome (RPLS) is a relatively recently characterised neurological syndrome, first described by Hinchey et al in 1996, with neuroimaging findings of reversible vasogenic subcortical oedema. The clinical presentation can vary, is often non-specific but can include headache, global encephalopathy, seizures and visual disturbances. In this article we present such a case in a 79 year old woman, followed by a discussion of the typical presentations, associations, pathomechanisms and neuroimaging findings.
可逆性后部白质脑病综合征(RPLS)是一种相对较新被描述的神经综合征,于1996年由欣奇等人首次描述,其神经影像学表现为可逆性血管源性皮质下水肿。临床表现可能各异,通常不具有特异性,但可包括头痛、全身性脑病、癫痫发作和视觉障碍。在本文中,我们介绍了一名79岁女性的此类病例,随后讨论了其典型表现、关联因素、发病机制和神经影像学发现。