Heinik Jeremia, Shaikewitz Dimitri
Margoletz Psychogeriatric Center, Ichilov Hospital, Tel Aviv 64239, Israel.
J Geriatr Psychiatry Neurol. 2009 Sep;22(3):171-80. doi: 10.1177/0891988709332940. Epub 2009 Mar 10.
This study examined the accuracy of the Clock Drawing Test--Modified and Integrated Approach (CDT-MIA) alone and combined with the Mini-Mental State Examination (MMSE) to detect Mild Cognitive Impairment (MCI) in patients with suspected MCI. For comparison, the accuracy of the Cambridge Cognitive Examination-Revised (CAMCOG-R) was tested. A total of 65 elderly outpatients with suspected MCI underwent a comprehensive evaluation. Following assessment, the entire sample was classified into: dementia (mild)--24 participants, MCI--22 participants, no cognitive impairment (NCI)--19 participants. CDT-MIA and the MMSE alone failed to appropriately discriminate demented from nondemented (MCI and NCI) and MCI from NCI. The best acceptable diagnostic accuracy to discriminate between demented and nondemented was obtained with CDT-MIA/MMSE combined and with CAMCOG-R. CDT-MIA/MMSE combined failed to appropriately discriminate MCI from NCI. The best diagnostic accuracy in this regard was obtained with CAMCOG-R.
本研究考察了改良整合版钟表绘制测试（CDT-MIA）单独使用以及与简易精神状态检查表（MMSE）联合使用时，在疑似轻度认知障碍（MCI）患者中检测MCI的准确性。作为比较，还测试了修订版剑桥认知检查表（CAMCOG-R）的准确性。共有65名疑似MCI的老年门诊患者接受了全面评估。评估后，整个样本被分为：轻度痴呆——24名参与者，MCI——22名参与者，无认知障碍（NCI）——19名参与者。单独使用CDT-MIA和MMSE无法准确区分痴呆患者与非痴呆患者（MCI和NCI），也无法区分MCI与NCI。CDT-MIA/MMSE联合使用以及CAMCOG-R在区分痴呆患者与非痴呆患者方面获得了最佳可接受诊断准确性。CDT-MIA/MMSE联合使用无法准确区分MCI与NCI。在这方面，CAMCOG-R获得了最佳诊断准确性。
