亚洲人种与骨关节炎全膝关节置换人群中代谢综合征的患病率。
Asian ethnicity and the prevalence of metabolic syndrome in the osteoarthritic total knee arthroplasty population.
机构信息
Division of Orthopedic Surgery, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.
出版信息
J Arthroplasty. 2010 Apr;25(3):416-9. doi: 10.1016/j.arth.2009.02.005. Epub 2009 Mar 10.
Metabolic syndrome (MS) is a known risk factor for the development of osteoarthritis (OA). We asked whether the prevalence of MS varies across ethnicity among patients who undergo total knee arthroplasty for end-stage OA. In our population of 1460 patients undergoing primary knee arthroplasty, MS was defined as body mass index greater than 30 kg/m(2), diabetes, hypertension, and hypercholesterolemia. Among the 1334 white patients, 114 (8.5%) had MS as compared with 3 of 36 (8.3%) blacks and 18 of 90 (20%) Asians (P = .006) Adjusted analysis showed that those of Asian ethnicity had a 2.0 (95% confidence interval, 1.1-3.8; P = .03) times greater odds of MS as compared with those of other ethnicity. Metabolic syndrome is a risk factor for OA, and Asians demonstrate a greater prevalence of MS as compared with whites and blacks in this population.
代谢综合征（MS）是骨关节炎（OA）发展的已知危险因素。我们想知道在因终末期 OA 而接受全膝关节置换术的患者中，MS 的患病率是否因种族而异。在我们的 1460 名接受初次膝关节置换术的患者中，MS 定义为体重指数大于 30kg/m²、糖尿病、高血压和高胆固醇血症。在 1334 名白人患者中，有 114 例（8.5%）患有 MS，而黑人 36 例中有 3 例（8.3%），亚洲人 90 例中有 18 例（20%）（P=0.006）。调整分析显示，与其他种族相比，亚洲人种患 MS 的几率高出 2.0 倍（95%置信区间，1.1-3.8；P=0.03）。代谢综合征是 OA 的一个危险因素，在该人群中，亚洲人比白人和黑人更普遍患有 MS。
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