Taner Timucin, Cima Robert R, Larson David W, Dozois Eric J, Pemberton John H, Wolff Bruce G
Division of Gastrointestinal and General Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Dis Colon Rectum. 2009 Feb;52(2):349-54. doi: 10.1007/DCR.0b013e31819a3e69.
Parastomal hernias occur frequently in patients with inflammatory bowel disease who require a stoma and are associated with high recurrence rates. The tissue weakness at the site of hernia can be overcome by creating neofascia using two separate layers of human acellular dermal matrix.
Thirteen consecutive patients with inflammatory bowel disease with symptomatic parastomal hernia underwent open parastomal hernia repair at an academic tertiary referral center whereby the posterior and anterior rectus fascia at the stoma site was reconstructed with human acellular dermal matrix. Patients were followed prospectively for 290 +/- 119 days (mean +/- standard deviation), and data were reviewed for rate of postoperative complications, hernia recurrence, and patient satisfaction.
Mean operative time was 233 +/- 80 (range, 129-355) minutes. No intraoperative complications occurred. Average hospital stay was 8.1 +/- 2.4 (range, 6-14) days. Postoperative complications included seroma formation, incisional separation (2 patients each, 15.4 percent), and superficial wound infection (1 patient, 7.7 percent). There were two cases of asymptomatic hernia recurrence as determined by computerized tomography. These patients did not require any intervention. Overall patient satisfaction with the procedure was high.
In patients with parastomal hernia, reconstruction of the stoma site and abdominal wall with human acellular dermal matrix seems to be safe and results in high patient satisfaction.
造口旁疝在需要造口的炎症性肠病患者中频繁发生,且复发率高。通过使用两层单独的人脱细胞真皮基质创建新筋膜可克服疝部位的组织薄弱问题。
在一家学术性三级转诊中心,对13例患有症状性造口旁疝的炎症性肠病患者进行了开放性造口旁疝修补术,术中使用人脱细胞真皮基质重建造口部位的腹直肌前后筋膜。对患者进行了为期290±119天(平均±标准差)的前瞻性随访,并对术后并发症发生率、疝复发情况及患者满意度数据进行了评估。
平均手术时间为233±80(范围129 - 355)分钟。术中无并发症发生。平均住院时间为8.1±2.4(范围6 - 14)天。术后并发症包括血清肿形成、切口裂开(各2例,15.4%)和浅表伤口感染(1例,7.7%)。计算机断层扫描确定有2例无症状疝复发。这些患者无需任何干预。总体而言,患者对该手术的满意度较高。
对于造口旁疝患者,用人脱细胞真皮基质重建造口部位和腹壁似乎是安全的,且患者满意度较高。