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一名6岁男孩促结缔组织增生性非婴儿型节细胞胶质瘤的病例报告及文献复习

A report of a desmoplastic non-infantile ganglioglioma in a 6-year-old boy with review of the literature.

作者信息

Per Hüseyin, Kontaş Olgun, Kumandaş Sefer, Kurtsoy Ali

机构信息

Department of Pediatric Neurology, Medical Faculty, Erciyes University, Kayseri, Turkey.

出版信息

Neurosurg Rev. 2009 Jul;32(3):369-74; discussion 374. doi: 10.1007/s10143-009-0195-3. Epub 2009 Mar 12.

Abstract

Desmoplastic infantile gangliogliomas (DIG) are uncommon supratentorial brain tumors with a usually good prognosis despite an aggressive radiological appearance that typically occurs in infants below the age of 24 months. DIGs are exclusively supratentorial, generally have a voluminous size, and are partially cystic. Total surgical removal is sufficient for the treatment of these tumors, and no chemotherapy or radiotherapy is indicated if complete resection is achieved. Except for age difference, DIG and desmoplastic non-infantile gangliogliomas are radiologically and histologically similar. Non-infantile variants of this biologically benign intracranial neoplasm are rare; only 15 cases of non-infantile DIGs have been reported in the literature. As far as we know, this case is the 16th in literature. We reported the magnetic resonance imaging and histological findings of desmoplastic ganglioglioma in a 6-year-old boy.

摘要

促纤维增生性婴儿型节细胞胶质瘤(DIG)是一种罕见的幕上脑肿瘤,尽管其影像学表现具有侵袭性,但通常预后良好,多见于24个月以下的婴儿。DIG仅发生于幕上,通常体积较大,部分为囊性。手术全切足以治疗这些肿瘤,若实现完全切除,则无需化疗或放疗。除年龄差异外,DIG与促纤维增生性非婴儿型节细胞胶质瘤在影像学和组织学上相似。这种生物学行为良性的颅内肿瘤的非婴儿型变体很罕见;文献中仅报道了15例非婴儿型DIG。据我们所知,本病例是文献报道的第16例。我们报告了一名6岁男孩促纤维增生性节细胞胶质瘤的磁共振成像和组织学表现。

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