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既往腹部手术、腹膜炎及粘连对腹膜透析导管功能及长期预后的影响。

Effect of prior abdominal surgery, peritonitis, and adhesions on catheter function and long-term outcome on peritoneal dialysis.

作者信息

Crabtree John H, Burchette Raoul J

机构信息

Department of Surgery, Southern California Permanente Medical Group, Kaiser Permanente Bellflower Medical Center, Bellflower, California 90706, USA.

出版信息

Am Surg. 2009 Feb;75(2):140-7. doi: 10.1177/000313480907500206.

DOI:10.1177/000313480907500206
PMID:19280807
Abstract

Adhesions from previous surgery and peritonitis can lead to peritoneal dialysis catheter insertion failure, visceral injury, and poor dialysis function. Employing a laparoscopic approach, the effect of adhesiolysis on mechanical catheter complications and long-term catheter survival was prospectively examined in 436 catheter placement procedures having a 57.8 per cent prevalence rate of previous surgery. Adhesiolysis was required in 31.8 per cent of cases with prior surgery and in 3.3 per cent of procedures without previous operations. The incidence of adhesiolysis was directly related to the number of prior surgeries (P < 0.0001). The incidence of catheter insertion failure from extensive adhesions was 1.8 per cent. Survival probability free from catheter obstruction was lower in patients requiring adhesiolysis compared with subjects with prior surgery not requiring adhesiolysis (P = 0.01). Laparoscopic rescue procedures limited catheter losses from flow obstruction to only 0.7 per cent. As a result, long-term catheter survival was not different among patients regardless of prior surgery and/or adhesion status (P = 0.2). Scars on the abdomen and prior peritonitis do not predict the extent of adhesions and should not be used to judge eligibility for peritoneal dialysis. Presently, laparoscopy is the only practical way to provide optimal peritoneal access in patients with a history of surgery and peritonitis.

摘要

既往手术和腹膜炎导致的粘连可致使腹膜透析导管置入失败、内脏损伤及透析功能不佳。采用腹腔镜方法,在436例导管置入手术中前瞻性地研究了粘连松解对机械性导管并发症和导管长期存活的影响,这些手术中既往手术的发生率为57.8%。在有既往手术的病例中,31.8%需要进行粘连松解,在无既往手术的手术中,这一比例为3.3%。粘连松解的发生率与既往手术次数直接相关(P<0.0001)。因广泛粘连导致的导管置入失败发生率为1.8%。与不需要粘连松解的既往手术患者相比,需要粘连松解的患者无导管梗阻的存活概率更低(P=0.01)。腹腔镜挽救手术将因流量梗阻导致的导管丢失率仅限制在0.7%。因此,无论既往手术情况和/或粘连状态如何,患者的导管长期存活情况并无差异(P=0.2)。腹部瘢痕和既往腹膜炎并不能预测粘连的程度,也不应被用于判断腹膜透析的适应证。目前,腹腔镜检查是为有手术史和腹膜炎的患者提供最佳腹膜通路的唯一实用方法。

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