Hirobe T, Takeuchi T
J Embryol Exp Morphol. 1977 Feb;37(1):79-90.
The number of melanocytes positive to the dopa reaction in the epidermis was shown to increase after newborn mice were injected with alpha-MSH or DBc-AMP. The agents seemed to induce the initiation of melanogenesis in the pre-existing melanoblasts. Electron-microscopic observation also demonstrated that alpha-MSH induced not only maturation of melanosomes but also the formation of melanosomes.
给新生小鼠注射α-促黑素(α-MSH)或二丁酰环磷腺苷(DBc-AMP)后,表皮中对多巴反应呈阳性的黑素细胞数量增加。这些药物似乎能诱导已存在的成黑素细胞开始黑素生成。电子显微镜观察还表明,α-MSH不仅能诱导黑素小体成熟,还能诱导黑素小体形成。