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促黑素细胞激素对新生小鼠皮肤表皮黑素母细胞黑素生成的诱导作用。

Induction of melanogenesis in the epidermal melanoblasts of newborn mouse skin by MSH.

作者信息

Hirobe T, Takeuchi T

出版信息

J Embryol Exp Morphol. 1977 Feb;37(1):79-90.

PMID:192826
Abstract

The number of melanocytes positive to the dopa reaction in the epidermis was shown to increase after newborn mice were injected with alpha-MSH or DBc-AMP. The agents seemed to induce the initiation of melanogenesis in the pre-existing melanoblasts. Electron-microscopic observation also demonstrated that alpha-MSH induced not only maturation of melanosomes but also the formation of melanosomes.

摘要

给新生小鼠注射α-促黑素(α-MSH)或二丁酰环磷腺苷(DBc-AMP)后,表皮中对多巴反应呈阳性的黑素细胞数量增加。这些药物似乎能诱导已存在的成黑素细胞开始黑素生成。电子显微镜观察还表明,α-MSH不仅能诱导黑素小体成熟,还能诱导黑素小体形成。

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