芬顿试剂对不同实验动物胃酸分泌的抑制作用。
Inhibitory effect of fentonium on gastric acid secretion in different laboratory animals.
作者信息
Impicciatore M, Morini G, Cavaggioni A L, Bertaccini G
出版信息
Farmaco Sci. 1977 Jul;32(7):482-9.
PMID:19285
Abstract
The influence of fentonium, a new derivative of hyoscyamine, on the gastric secretion has been evaluated in rats, cats and dogs. The compound appeared to be able to markedly reduce the gastric hypersecretion produced by pentagastrin, caerulein and bethanechol; its antagonizing activity against histamine stimulation was poor.
摘要
已在大鼠、猫和狗身上评估了一种新的东莨菪碱衍生物芬托铵对胃液分泌的影响。该化合物似乎能够显著减少由五肽胃泌素、蛙皮素和氨甲酰甲胆碱引起的胃酸分泌过多；但其对组胺刺激的拮抗活性较差。
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