可卡因相关梅毒疫情中的公共卫生干预措施。
Public health intervention in a cocaine-related syphilis outbreak.
作者信息
Hibbs J R, Gunn R A
机构信息
Epidemiology Program Office, Centers for Disease Control, Atlanta, Ga.
出版信息
Am J Public Health. 1991 Oct;81(10):1259-62. doi: 10.2105/ajph.81.10.1259.
BACKGROUND
Cocaine users and prostitutes are at high risk for syphilis, but disease control is difficult among these populations. During a cocaine-related syphilis outbreak in Chester, Pennsylvania, in 1989, we conducted a control program at sites where sex and drugs were sold.
METHODS
During a 2-week period, investigators recruited persons from these sites for interview, serologic testing, and empiric treatment.
RESULTS
Among 136 persons screened, 25 (18%) had early syphilis and 26 others (19%) had recent sexual contact with early syphilis patients. All were treated at initial screening at a cost of $402 and 12 investigator hours per case, compared to $470 and 20 hours per case when treated during routine investigator activities. This program may have contributed to a short-term decline in syphilis incidence in Chester by reducing the period of infectivity of these patients.
CONCLUSIONS
Screening and empiric treatment of persons at sites where sex and drugs are sold can be useful in short-term control of cocaine-related syphilis outbreaks.
背景
可卡因使用者和妓女感染梅毒的风险很高，但在这些人群中疾病控制很困难。1989年在宾夕法尼亚州切斯特发生与可卡因相关的梅毒疫情期间，我们在性交易和毒品交易场所开展了一项控制计划。
方法
在为期2周的时间里，研究人员从这些场所招募人员进行访谈、血清学检测和经验性治疗。
结果
在接受筛查的136人中，25人（18%）患有早期梅毒，另外26人（19%）近期与早期梅毒患者有性接触。所有患者在初次筛查时均接受了治疗，每例成本为402美元，每位研究人员花费12小时，而在常规研究活动中治疗时每例成本为470美元，每位研究人员花费20小时。该计划可能通过缩短这些患者的传染期，促使切斯特梅毒发病率出现短期下降。
结论
在性交易和毒品交易场所对人员进行筛查和经验性治疗，有助于短期内控制与可卡因相关的梅毒疫情。
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