Greenberg M S, Singh T, Htoo M, Schultz S
Epidemiology Service, New York City Department of Health, NY 10013.
Am J Public Health. 1991 Oct;81(10):1316-8. doi: 10.2105/ajph.81.10.1316.
From 1987 to 1989, an epidemic of congenital syphilis was observed in New York City. A case-control study was done to assess the association between various maternal risk factors and congenital syphilis. Independent of the effect of other factors, the odds of being exposed to cocaine were 3.9 times greater among cases than controls (95% confidence interval, 2.8-5.3). This study suggests that the epidemic of congenital syphilis may be related to the increase in cocaine/crack use among delivering mothers.
1987年至1989年期间,纽约市出现了先天性梅毒疫情。开展了一项病例对照研究,以评估各种孕产妇风险因素与先天性梅毒之间的关联。独立于其他因素的影响,病例组接触可卡因的几率比对照组高3.9倍(95%置信区间为2.8至5.3)。这项研究表明,先天性梅毒疫情可能与分娩母亲中可卡因/强效纯可卡因使用量的增加有关。