中脑对厌恶事件的信号传递：比预期更糟。

Signaling aversive events in the midbrain: worse than expected.

作者信息

Quirk Gregory J, Sotres-Bayon Francisco

机构信息

Departments of Psychiatry and Anatomy and Neurobiology, University of Puerto Rico School of Medicine, San Juan, PR 00936.

出版信息

Neuron. 2009 Mar 12;61(5):655-6. doi: 10.1016/j.neuron.2009.02.016.

DOI:10.1016/j.neuron.2009.02.016

PMID:19285461

Abstract

Although we know a great deal about how the brain processes information about aversive and appetitive stimuli, it is not clear how these two systems interact to guide behavior. In this issue of Neuron, Jhou and colleagues identify a region in the midbrain tegmentum that signals aversive events and inhibits midbrain dopamine neurons.

摘要

尽管我们对大脑如何处理有关厌恶和喜好刺激的信息已经了解很多，但尚不清楚这两个系统如何相互作用以指导行为。在本期《神经元》杂志中，Jhou及其同事确定了中脑被盖中的一个区域，该区域发出厌恶事件的信号并抑制中脑多巴胺能神经元。