Hashimoto K, Takeuchi Y, Takashima S
Division of Neonatology, Matsudo City Hospital, Chiba, Japan.
Brain Dev. 1991 May;13(3):155-7. doi: 10.1016/s0387-7604(12)80021-0.
In neonates pontosubicular necrosis (PSN) is one of the patterns of acute brain injury, the sites of maximum damage being the basis pontis and the subiculum of the hippocampus. A retrospective clinical and pathological study was performed on 16 preterm and 2 term neonates with PSN and compared with 16 age-matched controls. The results indicated that hypocarbia of less than 20 mmHg was one of the important factors in the pathogenesis of PSN.
