Deneuville T, Tance Y, Tiev K, Cervera P, Chanal J, Tolédano C, Gain M, Josselin L, Cabane J, Kettaneh A
Service de médecine interne, hôpital Saint-Antoine, université Pierre-et-Marie-Curie, 184 rue du Faubourg-Saint-Antoine, Paris cedex, France.
Rev Med Interne. 2009 Nov;30(11):982-4. doi: 10.1016/j.revmed.2009.01.013. Epub 2009 Mar 14.
Cholesterol crystal embolism is observed in polyvascular patients usually following a medical procedure. We report a 93-year-old patient with lower limb mononeuropathy in whom cholesterol crystal embolism was confirmed by neuromuscular biopsy. Previously, an ophthalmoscopy and a livedo biopsy had been performed and the results were normal. Mononeuropathy simplex or multiplex is a clinical expression for cholesterol crystal embolism that may thus be confounded with polyarteritis nodosa. Neuromuscular biopsy can provide accurate diagnosis if other investigations are inconclusive.
胆固醇结晶栓塞通常在接受医疗程序后的多血管患者中观察到。我们报告了一名93岁患有下肢单神经病的患者，其胆固醇结晶栓塞通过神经肌肉活检得到证实。此前，已进行了眼底检查和青斑活检，结果均正常。单纯性或多发性单神经病是胆固醇结晶栓塞的一种临床表现，因此可能与结节性多动脉炎混淆。如果其他检查结果不明确，神经肌肉活检可提供准确诊断。
