National Reference Centre for Bacterial Meningitis, Department of Epidemiology and Clinical Microbiology, National Medicines Institute, Chełmska 30/34 Street, 00-725 Warsaw, Poland.
Int J Infect Dis. 2009 Nov;13(6):e470-2. doi: 10.1016/j.ijid.2009.01.001. Epub 2009 Mar 14.
A rare case of peritonitis due to beta-lactamase-negative, ampicillin-resistant Haemophilus influenzae is described in an 18-year-old male undergoing automated peritoneal dialysis. The infection was probably of respiratory origin. Two strains of H. influenzae cultured from peritoneal fluid and a nasal swab were indistinguishable by molecular methods. The patient was successfully treated with oral ciprofloxacin. The authors suggest that this species should be taken into account as the etiologic agent of peritoneal dialysis-associated peritonitis. Targeted antimicrobial therapy should be based on local antibiotic resistance patterns.
本文描述了 18 岁男性在接受自动化腹膜透析时发生的由β-内酰胺酶阴性、氨苄西林耐药流感嗜血杆菌引起的罕见腹膜炎。感染可能来源于呼吸道。从腹腔液和鼻拭子中培养的两种流感嗜血杆菌通过分子方法无法区分。患者经口服环丙沙星成功治疗。作者建议将该物种视为与腹膜透析相关腹膜炎的病原体。靶向抗菌治疗应基于局部抗生素耐药模式。