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肽可识别光响应靶点。

Peptides recognize photoresponsive targets.

作者信息

Chen Jing, Serizawa Takeshi, Komiyama Makoto

机构信息

Department of Chemistry and Biotechnology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan.

出版信息

Angew Chem Int Ed Engl. 2009;48(16):2917-20. doi: 10.1002/anie.200900115.

Abstract

Clones on film: 7-mer peptides that bind to azobenzene-containing polymer films were selected from a phage library under visible light. Isolated clones showed greater affinities to the films under ultraviolet light than those under visible light. Furthermore, the peptide binding responds to the photoinduced isomerization of azobenzene groups.

摘要

薄膜上的克隆

在可见光下从噬菌体文库中筛选出与含偶氮苯聚合物薄膜结合的七聚体肽。分离出的克隆在紫外光下对薄膜的亲和力比在可见光下更高。此外,肽的结合对偶氮苯基团的光致异构化有响应。

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