Liu Ben, Zhu Xuan-Wen, Zhong Da-Chuan, Shen Bo-Hua, Jiang Hai, Xie Li-Ping
Department of Urology, The First Hospital Affiliated to Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, China.
Zhonghua Nan Ke Xue. 2009 Jan;15(1):45-7.
To evaluate the clinical results of the replacement of plaque by buccal mucosa in the treatment of Peyronie's disease.
We performed surgical replacement of the plaque by free autograft of buccal mucosa on 27 patients with Peyronie's disease, ranging in age from 24 to 72 years (mean 53), varying in disease course between 1 and 13 years, with a penile curvature angle of 30 degrees - 80 degrees in erection. Of the total number, 15 patients had the plaque located in the dorsal root, 6 in the dorsal shaft, 3 in the subcoronal shaft and 3 in the ventral shaft of the penis; 24 had 1 plaque, 2 had 2 and 1 had 3, ranging in size from 0.7 cm x 0.7 cm to 1.6 cm x 1.0 cm.
Satisfactory results were achieved in all the cases, with no such complications as hematoma, infection, oral numbness, and tightness of the mouth. Of the 24 cases that were followed up for 0.5 to 7 years, complete straightening of the penis was achieved in 21, slight residual curvature (< 15 degrees) was noted in 3, a little shortening of the penis (< 1 cm) in 2, and erectile pain in 3.
Buccal mucosa, with a stable elasticity and no shrinkage, can be recommended for wide use in the surgical treatment of Peyronie's disease.
评估采用颊黏膜替代斑块治疗佩罗尼氏病的临床效果。
我们对27例佩罗尼氏病患者进行了颊黏膜游离自体移植替代斑块的手术，患者年龄在24至72岁之间（平均53岁），病程在1至13年之间，勃起时阴茎弯曲角度为30度至80度。其中，15例患者的斑块位于阴茎背侧根部，6例位于阴茎背侧体部，3例位于阴茎冠状沟下，3例位于阴茎腹侧体部；24例患者有1个斑块，2例有2个，1例有3个，斑块大小从0.7厘米×0.7厘米至1.6厘米×1.0厘米不等。
所有病例均取得满意效果，未出现血肿、感染、口腔麻木及口腔紧绷等并发症。在24例随访0.5至7年的病例中，21例阴茎完全伸直，3例有轻微残余弯曲（<15度），2例阴茎稍有缩短（<1厘米），3例有勃起疼痛。
颊黏膜弹性稳定且无收缩，可推荐广泛应用于佩罗尼氏病的手术治疗。
