Zhou Hai-Jun, Lu Hong-Kai
Department of Urology, Weifang TCM Hospital, Weifang, Shandong 261041, China.
Zhonghua Nan Ke Xue. 2009 Jan;15(1):65-8.
By studying the novel methods for reconstructing damaged cavernous nerves and the related literature on the regeneration of cavernous nerves, restoration of erectile function and neurohistological reconstruction engineering, a variety of grafting materials have been found applicable to cavernous nerve reconstruction, including autogenetic nerve grafts, silicone tubes, artificial biodegradable conduits and so on. Neurotrophic factors, extra cellular matrix components and Schwann cells have been shown to promote cavernous regeneration. Artificial nerve guides, especially biodegradable ones containing growth-promoting factors or cells, are a promising option for the repair of cavernous nerve lesions.
通过研究修复受损海绵体神经的新方法以及海绵体神经再生、勃起功能恢复和神经组织学重建工程的相关文献,已发现多种移植材料适用于海绵体神经重建,包括自体神经移植物、硅胶管、人工可生物降解导管等。神经营养因子、细胞外基质成分和雪旺细胞已被证明可促进海绵体再生。人工神经导管,尤其是含有促进生长因子或细胞的可生物降解导管,是修复海绵体神经损伤的一个有前景的选择。