Ahmad Iftikhar, Saeed Usman, Rehmani Rifat, Ahmed Muhammad Ejaz
Department of Radiology, Shaukat Khanum Memorial Cancer Hospital and Research Center, Pakistan.
J Pak Med Assoc. 2009 Mar;59(3):179-81.
Primary bone lymphoma (PBL) is an uncommon tumour. Numerous studies have been reported from Western countries, but none from Southeast Asia. We reviewed a series of seven consecutive patients diagnosed and treated with PBL at our hospital between March 2002 and January 2007. All patients underwent chemotherapy with half receiving radiotherapy as their initial treatment. Six (84%) patients were male and 1 (16%) female with a median age of 33 (range: 23-85). All had diffuse large B-cell lymphoma (DLBCL) of bone except one (85 - M) who had chest wall cutaneous T-cell lymphoma with iliac blade involvement. The femur was the most frequently involved site (43%). Except for three patients that involved the lymph nodes, all patients had disease limited to bone. The 5-year overall survival rate was 43%. Although the number of patients was small, the data presented here revealed several characteristics of PBL.
原发性骨淋巴瘤（PBL）是一种罕见的肿瘤。西方国家已报道了许多相关研究，但东南亚地区尚无此类报道。我们回顾了2002年3月至2007年1月期间在我院连续诊断和治疗的7例PBL患者。所有患者均接受了化疗，其中一半患者初始治疗时接受了放疗。6例（84%）患者为男性，1例（16%）为女性，中位年龄为33岁（范围：23 - 85岁）。除1例（85 - M）患者为胸壁皮肤T细胞淋巴瘤伴髂骨受累外，其余所有患者均为骨弥漫性大B细胞淋巴瘤（DLBCL）。股骨是最常受累的部位（43%）。除3例患者累及淋巴结外，所有患者的疾病均局限于骨骼。5年总生存率为43%。尽管患者数量较少，但此处呈现的数据揭示了PBL的几个特征。
