Mpairamidis Evriviadis, Alexiou George A, Stefanaki Kalliopi, Manolakos Ilias, Sfakianos George, Prodromou Neofytos
Department of Neurosurgery, Childrens Hospital Agia Sofia, Athens, Greece.
Brain Pathol. 2009 Apr;19(2):341-2. doi: 10.1111/j.1750-3639.2009.00278.x.
Cerebellar glioblastoma multiforme (GBM) has rarely been reported in children. We report a case of a 12-year-old child complaining of right upper limb tremor, loss of the normal capacity to modulate fine voluntary movements with right hand and headache, lasting for over a month. Radiological studies (CT and MRI) revealed a lesion of the right cerebellar hemisphere. The tumor was surgically excised and the histological examination revealed the presence of a GBM. The differential diagnosis of the lesions in the posterior fossa should include GBM. A gross total resection should be always attempted in order to achieve a better clinical outcome, although nearly all of these tumors recur.
儿童小脑多形性胶质母细胞瘤(GBM)鲜有报道。我们报告一例12岁儿童,主诉右上肢震颤、右手精细自主运动调节能力丧失及头痛,持续一个多月。影像学检查(CT和MRI)显示右小脑半球有病变。肿瘤经手术切除,组织学检查显示为GBM。后颅窝病变的鉴别诊断应包括GBM。尽管几乎所有这些肿瘤都会复发,但为了获得更好的临床结果,应始终尝试进行全切除。