核苷的染料标记
Dye labelling of nucleosides.
作者信息
Katritzky Alan R, Khelashvili Levan, Kovacs Judit, Shanab Karem
机构信息
Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA.
出版信息
Chem Biol Drug Des. 2009 Apr;73(4):396-402. doi: 10.1111/j.1747-0285.2009.00792.x.
Abstract
Dye-labelled nucleosides were obtained in 30-79% (average 45%) yields by treating N-(4-arylazobenzoyl)-1H-benzotriazoles 3a-b with appropriate nucleosides. Similarly, 3a-b afforded dye-labelled threoninol conjugates in 55-89% (average 67%) yields. All novel products were characterized by NMR and elemental analysis.
摘要
通过用适当的核苷处理N-(4-芳基偶氮苯甲酰基)-1H-苯并三唑3a-b，以30-79%（平均45%）的产率获得了染料标记的核苷。类似地，3a-b以55-89%（平均67%）的产率提供了染料标记的苏氨醇缀合物。所有新产物均通过核磁共振和元素分析进行了表征。
Zotero 插件